Weird idea about compression

Instead of a standard palette, why not just build one from your sprites/tiles? That’s what I did in my demo: added all the sprites/tiles into a single image in aseprite, changed from RGBA to Indexed, exported the PAL.
I guess you could use RGB332/RGB233/RGB242/etc as a general purpose palette, but that might have problems with certain colors.
@spinal: Your palette has no gray?

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need a pallet to be used by more then 1 artist for a project and i dont want 2 reds that basicly look the same on screen take up 2 pallet slots

Make a palette from a few reference images and then use that?

As @adekto mentioned, there are 4 spare indexes. Use 3 of them for grey, use the last one for transparency.